Endocrine Abstracts

A recent audit of the urine steroid profile (USP) service at Glasgow Royal Infirmary (GRI) revealed that up to 25% of requests are made inappropriately, or without any clinical information. In contrast to the majority of biochemical testing, USP analysis is very labour intensive, and interpretation of results requires both quantitative and qualitative assessment of the profile. Adequate clinical information is essential to generate a complete report, as a number of steroids fo...

Case: A 33 year old gentleman presented with significantly raised testosterone levels, testicular pain, erectile dysfunction and weight loss. He denied use of anabolic steroids. Upon physical examination he looked muscular and tanned. Left testicle was tender with no palpable mass. Raised androgen levels (Siemens immunoassay) were confirmed by liquid chromatography tandem mass spectrometry (LC-MS/MS), ruling out assay interference. In view of his ongoing denial of substance mi...

Case: A 33 year old gentleman presented with significantly raised testosterone levels, testicular pain, erectile dysfunction and weight loss. He denied use of anabolic steroids. Upon physical examination he looked muscular and tanned. Left testicle was tender with no palpable mass. Raised androgen levels (Siemens immunoassay) were confirmed by liquid chromatography tandem mass spectrometry (LC-MS/MS), ruling out assay interference. In view of his ongoing denial of substance mi...